Scientists Use Gene Therapy to Restore Vision in Mice

by Ophthalmology Associates / 03 October 2017 / No Comments

The three blind mice may be blind no more thanks to a new medical breakthrough!

Scientists at a number of research facilities including Stanford Medical, the Vision Institute at Sorbonne University, and the National Institute of Health and Medicine have managed to reverse blindness in mice.

The Studies

In the Stanford study, scientists experimented with ways to reestablish the optic nerve connection and found success in a combination of gene and visual stimulation therapies.

  • While their vision was not fully restored, the mice were once again able to make out shadows, which would be roughly equivalent to a human regaining the ability to see large objects and grasp his or her positioning in a room.

The Vision Institute and National Institute of Health and Medicine, meanwhile, took a strictly genetic approach. They injected 70 mice that had or were predisposed to glaucoma with a single gene, Ngb (neuroglobin).

  • The fifty-five mice that received the Ngb injection at two months of age never developed glaucoma, and the eighteen mice injected at eight months of age saw the glaucoma reversed.

What Do These Findings Mean?

Glaucoma is a leading cause of blindness and is currently incurable, but the prevention and reversal of glaucoma in these mice is a very exciting development.

The results of the Stanford study show promise for combating a number of other eye diseases as well.

Many scientists are now optimistic that there will be new and effective treatments for human blindness within the next decade.

If you have glaucoma or are looking for a trusted eye care specialist in the Western New York area, Ophthalmology Associates of Western New York can help. Call us at 716-632-3545 or contact us online today to learn more and schedule your appointment.